(Inside Science) -- After the 2018 Nobel Prize in physics was announced this week, several stories appeared highlighting the fact that Donna Strickland of the University of Waterloo in Canada did her groundbreaking work while in graduate school.
It's uncommon to win what is arguably the highest achievement in science for work done as a graduate student, but definitely not unprecedented. Here is a look at five other laureates who won prizes for remarkable work they did as graduate students:
She coined the term "radioactivity"
The superlative list of achievements credited to Marie Curie is too long to describe here. She is the first woman to win a Nobel Prize, the first person to win more than one and the only woman to ever win twice. She coined the term radioactivity, and as a graduate student she isolated the radioactive elements radium and polonium. In 1903, the same year she was awarded her doctorate from the University of Paris, she won the Nobel Prize in physics with two others, her husband, Pierre Curie, and Antoine Henri Becquerel for their research on radiation.
He uncovered a cornerstone of quantum mechanics
Louis-Victor Pierre Raymond de Broglie boldly hypothesized in his 1924 doctoral thesis a flip side to Einstein's coin. Einstein had proposed that light waves could exhibit particlelike behavior, and de Broglie hypothesized, inversely, that particles of matter could have the properties of waves -- so-called particle-wave duality. The wavelike behavior of particles became a cornerstone of quantum mechanics and won de Broglie the Nobel Prize in physics in 1929 "for his discovery of the wave nature of electrons."
He established the mathematics of game theory
In 1950, John Nash graduated from Princeton University with a doctorate in mathematics and a thesis that bore the simple title, "Non-Cooperative Games." In it, he laid out the underpinnings of game theory, and in 1994 he won the Nobel Memorial Prize in Economic Sciences with John C. Harsanyi and Reinhard Selten for this work. His mathematical feats and later struggles with schizophrenia became subject of the Sylvia Nasar's book "A Beautiful Mind," which was adapted into a movie that won Oscars for both Russel Crowe and Ron Howard.
He discovered superfluidity in Helium-3 -- by accident
As unexpected as it was profound, the strange behavior in a sample of the isotope helium-3 at a temperature just above absolute zero was noticed by graduate student Douglas D. Osheroff in the early 1970s. What appeared at first to be a glitch turned out to be a new instance of superfluidity -- where atoms in the liquid move in a coordinated manner and exhibit nonclassical behavior. In 1996, Osheroff shared the Nobel Prize in physics with David M. Lee and Robert C. Richardson for this discovery.
She identified a crucial enzyme that protects DNA
Before getting her doctorate from the University of California, Berkeley in 1987, Carol W. Greider and her mentor Elizabeth H. Blackburn discovered an important enzyme called "telomerase." It makes telomeres, which cover the ends of DNA chromosomes to protect them -- not unlike the plastic tips atop shoelaces that keep the fabric from fraying over time. In 2009, Grieder won the Nobel Prize in physiology or medicine with Blackburn and Jack W. Szostak for their discoveries.
He was denied the prize despite spectacular success
Charles H. Best had just finished his undergraduate degree and was a 22-year-old research assistant in the laboratory of professor John J.R. Macleod at the University of Toronto in the early 1920s when he accomplished his most famous achievement. In just his first few months of work, he and a young surgeon named Frederick G. Banting discovered insulin. But it was Banting and Macleod who were awarded the 1922 Nobel Prize in physiology or medicine and not Best. (Banting famously shared his prize money with Best in protest.)
While Best never won the Nobel Prize, the value of his work for humanity is hard to ignore. Insulin turned diabetes from a death sentence into a manageable chronic disease almost overnight, and it has saved countless lives ever since.
For more of Inside Science's coverage of the 2018 Nobel Prizes in Physiology or Medicine, Physics, and Chemistry, please visit https://www.insidescience.org/nobel-coverage/2018.